Dopaminergic Neurotransmission in the Human Brain: New Lessons from Perturbation and Imaging
Identifieur interne : 001684 ( Main/Exploration ); précédent : 001683; suivant : 001685Dopaminergic Neurotransmission in the Human Brain: New Lessons from Perturbation and Imaging
Auteurs : Ji Hyun Ko [Canada] ; Antonio P. Strafella [Canada]Source :
- The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry [ 1073-8584 ] ; 2011.
Abstract
Dopamine plays an important role in several brain functions and is involved in the pathogenesis of several psychiatric and neurological disorders. Neuroimaging techniques such as positron emission tomography allow us to quantify dopaminergic activity in the living human brain. Combining these with brain stimulation techniques offers us the unique opportunity to tackle questions regarding region-specific neurochemical activity. Such studies may aid clinicians and scientists to disentangle neural circuitries within the human brain and thereby help them to understand the underlying mechanisms of a given function in relation to brain diseases. Furthermore, it may also aid the development of alternative treatment approaches for various neurological and psychiatric conditions.
Url:
DOI: 10.1177/1073858411401413
PubMed: 21536838
PubMed Central: 3479149
Affiliations:
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